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Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular types with recombination purpose.
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Our function was swiftly adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
This yielded a breakthrough. Inside only some months, we have been capable of evaluate transport by a person one-walled carbon nanotube. Depending on small-temperature experiments by a superb PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Microbiology has only existed for just a century, since we started to research micro-organisms a lot more significantly. I believed nanobiology was an acceptable expression, mainly because all molecular Organic suitable interactions happen for the nanoscale: a protein is some nanometres in dimensions, DNA is two nm thick.’
A lot of linked developments adopted, where by our group proven diverse transistor variants which include single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled many transistors into small proof-of-principle electronic circuits.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
The rotors harness Power from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical likely gradient inside the nanopore, that are established by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological disorders, suggesting solutions to constructing energy-transducing motors at nanoscale interfaces.
There was a person issue however — we didn't notice any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule degree, conducting polymers have been essentially not this kind of excellent conductors, which was somewhat disappointing. We So broadened our check out to try to seek out additional promising molecules.
An built-in microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes
2006, to start with demonstration of molecular sorting inside a lab over a chip applying biomotors; discovery of nanobubbles in sound-condition nanopores; and to start with estimate of electrokinetic Power conversion in the nanofluidic channel
Enable’s first appear back in the meanwhile after you made a decision to change your focus from superconductivity and nanotubes to biology at the end of the 1990s.
The biophysicist from Delft – who has become Among the most cited researchers inside the Netherlands For many years – requires his responsibility to add to your clarification and popularisation of his operate on the border of physics and biology very seriously and consistently seems https://www.ceesdekker.net inside the media; if not to look at his operate, then about the relationship between science and his Christian religion.